Hossein Ardeschir Ghofrani Selected Research

motapizone

7/2005

Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors.

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Hossein Ardeschir Ghofrani Research Topics

Disease

50	Pulmonary Hypertension 10/2022 - 04/2002
25	Pulmonary Arterial Hypertension 10/2022 - 04/2002
19	Hypoxia (Hypoxemia) 01/2022 - 01/2006
18	Vascular Remodeling 02/2021 - 04/2004
8	Fibrosis (Cirrhosis) 01/2018 - 09/2002
7	Familial Primary Pulmonary Hypertension 10/2022 - 07/2005
7	Cardiomegaly (Heart Hypertrophy) 10/2016 - 04/2004
6	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2022 - 11/2009
6	Heart Diseases (Heart Disease) 01/2022 - 09/2005
5	Lung Diseases (Lung Disease) 10/2022 - 11/2009
4	Hypertrophy 01/2018 - 08/2007
3	Pulmonary Heart Disease (Cor Pulmonale) 01/2022 - 04/2004
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 03/2014
3	Right Ventricular Hypertrophy 01/2020 - 01/2010
3	Idiopathic Pulmonary Fibrosis 01/2017 - 06/2011
3	Heart Failure 08/2016 - 01/2015
3	Neoplasms (Cancer) 01/2010 - 06/2007
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2012
2	Hypotension (Low Blood Pressure) 01/2021 - 04/2006
2	Emphysema 01/2019 - 01/2015
2	Body Weight (Weight, Body) 12/2018 - 06/2012
2	Lung Neoplasms (Lung Cancer) 11/2017 - 11/2009
2	Vascular Diseases (Vascular Disease) 11/2015 - 10/2005
1	Pulmonary edema of mountaineers 10/2021
1	Headache (Headaches) 01/2021
1	Cough 01/2021
1	Dyspepsia (Indigestion) 01/2021
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2021
1	Disease Progression 01/2021
1	Heart Neoplasms 01/2019
1	Ischemia 01/2017
1	Edema (Dropsy) 01/2017
1	Acute Lung Injury 01/2017
1	Ventricular Remodeling 11/2016

Drug/Important Bio-Agent (IBA)

15	MonocrotalineIBA 02/2021 - 04/2004
10	Sildenafil Citrate (Viagra)FDA Link 01/2018 - 04/2002
9	Iloprost (Ventavis)FDA Link 05/2010 - 04/2002
8	Soluble Guanylyl CyclaseIBA 01/2020 - 01/2006
7	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2015 - 04/2004
6	riociguatIBA 01/2021 - 04/2011
6	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2021 - 04/2002
6	Phosphodiesterase 5 InhibitorsIBA 01/2020 - 06/2005
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2015
5	Semaxinib (SU5416)IBA 01/2021 - 01/2012
4	Bleomycin (Blenoxane)FDA LinkGeneric 03/2022 - 06/2011
4	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2021 - 06/2005
4	Vasodilator Agents (Vasodilators)IBA 03/2020 - 04/2002
4	Oxygen (Dioxygen)IBA 12/2018 - 01/2006
4	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 09/2013
4	CollagenIBA 11/2015 - 11/2009
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 06/2012
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2005
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 12/2018 - 01/2012
3	EndotoxinsIBA 01/2017 - 04/2006
3	Chymases (Chymase)IBA 10/2015 - 01/2013
3	ProstaglandinsIBA 12/2012 - 07/2005
3	Imatinib Mesylate (Gleevec)FDA Link 06/2012 - 10/2005
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2012 - 09/2002
3	tolafentrineIBA 03/2011 - 04/2004
2	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 03/2022 - 01/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2018 - 11/2015
2	CytokinesIBA 11/2017 - 11/2009
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017 - 11/2009
2	TRPC6 Cation ChannelIBA 01/2017 - 12/2006
2	Tadalafil (Cialis)FDA Link 01/2015 - 08/2012
2	Small Interfering RNA (siRNA)IBA 09/2013 - 04/2011
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 06/2012 - 10/2005
2	Platelet-Derived Growth FactorIBA 06/2012 - 04/2012
2	Fibronectins (Fibronectin)IBA 04/2012 - 11/2009
2	diethylstilbestrol monophosphate (PDES)IBA 04/2011 - 01/2010
2	Phosphodiesterase InhibitorsIBA 01/2010 - 07/2005
2	Protein Isoforms (Isoforms)IBA 01/2010 - 11/2009
2	Vasoconstrictor AgentsIBA 10/2007 - 04/2006
2	15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidIBA 01/2006 - 07/2005
2	ThromboxanesIBA 01/2006 - 07/2005
1	Carbon MonoxideIBA 10/2022
1	Brain Natriuretic Peptide (Natrecor)FDA Link 10/2022
1	TransferasesIBA 01/2022
1	4-S-(propionic acid)sulfidocyclophosphamide (PASP)IBA 01/2022
1	GoldIBA 01/2022
1	Alanine Transaminase (SGPT)IBA 01/2022
1	jugloneIBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 01/2022
1	regorafenibIBA 02/2021
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021
1	Epoprostenol ReceptorsIBA 01/2021
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020
1	Endothelin Receptor AntagonistsIBA 01/2020
1	6-chloropenicillanic acid S-sulfoxideIBA 01/2019
1	nintedanibIBA 01/2018
1	Therapeutic UsesIBA 01/2017
1	17- (dimethylaminoethylamino)- 17- demethoxygeldanamycinIBA 01/2017
1	tanespimycin (17AAG)IBA 01/2017
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2017
1	Metalloproteases (Metalloproteinases)IBA 11/2016
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 10/2016

Therapy/Procedure

20	Therapeutics 10/2022 - 04/2002
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2010